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Endocrine Abstracts

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ea0071014 | Influence of catecholamine secretory phenotype and preoperative alpha-blocker preparation on surgical outcome in pheochromocytoma | BES2020

Influence of catecholamine secretory phenotype and preoperative alpha-blocker preparation on surgical outcome in pheochromocytoma

Maria Furnica Raluca , Muddaththir Dusoruth Muhammad , Damien Gruson , Alexandre Persu , Michel Mourad , Dominique Maiter

Objectives: Surgery of pheochromocytomas (PC) still carries a high risk of hemodynamic complications during the perioperative period. We aimed to evaluate the influence of their secretory phenotype and preoperative alpha-blocker treatment on surgical outcome.Design: A retrospective monocentric study at a tertiary medical center.Patients: 80 consecutive patients operated for an adrenal PC between 1988 and 2018.<p class="abstext"...
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ea0084op-05-22 | Oral Session 5: Autoimmunity | ETA2022

Update on the role of caveolin-1 in cell homeostasis and oxidative stress in hashimoto’s thyroiditis and graves’ disease

Many Marie-Christine , Daumerie Chantal , Boschi Antonella , lelio baldeschi , Michel Mourad , Lengele Benoit , Catherine Behets , Marique Lancelot , Van Regemorter Victoria , Alexis Werion , Regemorter Elliott Van , Michael Hepp , Bournonville Marc de , Ville de Goyet Christine de , Craps Julie

Caveolin-1 (cav1) is a member of the thyroxisome multiprotein complex required for thyroid hormones synthesis which is decreased in Hashimoto’s thyroiditis (HT) and excessive in Graves’ disease (GD). Both pathologies are characterized by oxidative stress (OS), the production of reactive oxygen species (ROS) exceeding the antioxidant defenses. The aim of this study is to correlate cav1 expression and OS in HT and GD. Primary cultures of human thyrocytes were treated o...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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